模型信息
中文名称:SARS-CoV F-mus-VeroE6滴鼻感染BALB/c小鼠模型
英文名称:SARS-CoV F-mus-VeroE6 intranasally infection BALB/c mouse model
类型:SARS-CoV感染动物模型
分级:NA
用途:用于SARS-CoV感染研究。
研制单位:国立感染症研究所@@https://www.niid.go.jp/
保存单位:国立感染症研究所@@https://www.niid.go.jp/
研究背景
暂无介绍
制备方法
Three hours after intranasal inoculation of F-musX-VeroE6 (2×10^6 TCID50 in 20μl), adult (6-month-old) BALB/c females mice were injected intravenously with 100μl of anti-mouse TNF- rat monoclonal antibody (1μg/μl, Biosource), or isotype-matched control rat antibody (1μg/μl; MP Biomedicals, Solon, OH) in PBS, or injected intraperitoneally with 100μl of recombinant mouse IFN-γ (0.05μg/μl; R&D Systems, Minneapolis, MN) or intraperitoneal injection with 100μl of PBS/0.1% bovine serum albumin was used as control. At least two independent experiments were performed (n=5 or 8 per group).
评价验证
暂无介绍
生物安全性
暂无介绍
讨论与结论
暂无介绍
了解中析
实验室仪器
合作客户
